Relative binding constants of arsenical-antidote adducts determined by NMR spectroscopy.

نویسندگان

  • R J O'Connor
  • E L McGown
  • K Dill
  • S F Hallowell
چکیده

Proton nuclear magnetic resonance spectroscopy was used to determine relative binding constants for several arsenical-antidote adducts. It was found that BAL (2,3-dimercaptopropanol) and DMPS (2,3-dimercaptopropanesulfonic acid) had a higher affinity than DMSA (2,3-dimercaptosuccinic acid) for the two organic arsenicals studied.

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عنوان ژورنال:
  • Research communications in chemical pathology and pharmacology

دوره 69 3  شماره 

صفحات  -

تاریخ انتشار 1990